Cancer Cell Metabolism

  • Nitisinone | Tyrosine metabolism inhibitor

    CAS:
    104206-65-7
    Catalog Number:
    10-4648
    Activity:
    Tyrosine metabolism inhibitor
    Chemical Names:
    2-[2-Nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione
    Alternate Name:
    NTBC
    Molecular Weight:
    329.23
    Molecular Formula:
    C14H10F3NO5
    Solubility:
    Soluble in DMSO (at least 70 mg/ml); ethanol (10 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $25.00
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  • Ophiobolin A | Autophagy inducer / Anticancer

    CAS:
    4611-05-6
    Catalog Number:
    10-3150
    Activity:
    Autophagy inducer / Anticancer
    Alternate Names:
    Cochliobolin A; Ophiobalin; NSC 114340
    Molecular Weight:
    400.55
    Molecular Formula:
    C25H36O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • Pemetrexed 2Na | Multitargeted antifolate

    CAS:
    357166-29-1
    Catalog Number:
    10-2162
    Activity:
    Multi-targeted antifolate
    Chemical Name:
    N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, disodium salt
    Molecular Weight:
    597.49
    Molecular Formula:
    C20H19N5O6 • 2Na • 7H2O
    Solubility:
    Soluble in Water (up to 100 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC and HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 31month.
    Shipping Code:
    RT
    From $70.00
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  • PF-06840003 | IDO1 inhibitor

    CAS:
    198474-05-4
    Catalog Number:
    10-4498
    Activity:
    IDO1 inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
    Alternate Name:
    EOS200271
    Molecular Weight:
    232.21
    Molecular Formula:
    C12H9FN2O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • PF-4708671 dihydrochloride | S6K1 inhibitor

    CAS:
    125517-76-0 (free base)
    Catalog Number:
    10-4856
    Activity:
    S6K1 inhibitor
    Chemical Names:
    2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzimidazole dihydrochloride
    Molecular Weight:
    463.33
    Molecular Formula:
    C19H21F3N6·2HCl
    Solubility:
    Soluble in DMSO (at least 35 mg/ml); Water (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month. Hygroscopic solid – protect from moisture.
    Shipping Code:
    RT
    From $40.00
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