Cellular Stress

  • Hydroxyurea | Anticancer agent

    CAS:
    127-07-1
    Catalog Number:
    10-3510
    Activity:
    Anticancer agent
    Chemical Names:
    N-Hydroxyurea; Hydroxycarbamide
    Molecular Weight:
    76.06
    Molecular Formula:
    CH4N2O2
    Solubility:
    Soluble in water (50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied from date of purchase. Solutions in water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $54.00
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  • Importazole | Blocks importin-ß-mediated nuclear import

    CAS:
    662163-81-7
    Catalog Number:
    10-1412
    Activity:
    Blocks importin-β-mediated nuclear import
    Alternate Names:
    IPZ
    Chemical Name:
    N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine
    Molecular Weight:
    318.43
    Molecular Formula:
    C20H22N4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Irinotecan HCl | Topoisomerase I inhibitor

    CAS:
    136572-09-3
    Catalog Number:
    10-2146
    Activity:
    Topoisomerase I inhibitor
    Chemical Name:
    (S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4′-bipiperidine]-1′-carboxylate hydrochloride
    Molecular Weight:
    677.2
    Molecular Formula:
    C33H38N4O6 HCl 3H2O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), in Water (up to 4 mg/ml) or in Ethanol (up to 4 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • KNK437 | HSP70 inhibitor

    CAS:
    218924-25-5
    Catalog Number:
    10-5561
    Activity:
    HSP70 inhibitor
    Chemical Names:
    3-(1,3-Benzodioxol-5-ylmethylene)-2-oxo-1-pyrrolidinecarboxaldehyde
    Molecular Weight:
    245.23
    Molecular Formula:
    C13H11NO4
    Solubility:
    Soluble in DMSO (30 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Luminespib | HSP90 inhibitor

    CAS:
    747412-49-3
    Catalog Number:
    10-4672
    Activity:
    HSP90 inhibitor
    Chemical Names:
    5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide
    Alternate Name:
    NVP-AUY922; VER-52296
    Molecular Weight:
    465.54
    Molecular Formula:
    C26H31N3O5
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page
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