Chemotherapeutics

  • Ruxolitinib | JAK inhibitor

    CAS:
    941678-49-5
    Catalog Number:
    10-4511
    Activity:
    JAK inhibitor
    Alternate Names:
    INCB 018424
    Chemical Name:
    βR-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
    Molecular Weight:
    306.37
    Molecular Formula:
    C17H18N6
    Solubility:
    Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • SAHA | HDAC inhibitor

    CAS:
    149647-78-9
    Catalog Number:
    10-1067
    Activity:
    HDAC inhibitor
    Alternate Names:
    Vorinostat
    Chemical Name:
    Suberoylanilide-hydroxamic acid
    Molecular Weight:
    264.33
    Molecular Formula:
    C14H20N2O3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
    Shipping Code:
    RT
    From $35.00
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  • Selpercatinib | Potent and selective RET kinase inhibitor

    CAS:
    2152628-33-4
    Catalog Number:
    10-4407
    View Product This product has multiple variants. The options may be chosen on the product page
  • SN-38 | DNA topoisomerase I inhibitor

    CAS:
    86639-52-3
    Catalog Number:
    10-2425
    Activity:
    DNA topoisomerase I inhibitor
    Chemical Name:
    7-Ethyl-10-hydroxycamptothecin
    Molecular Weight:
    392.41
    Molecular Formula:
    C22H20N2O5
    Solubility:
    Soluble in DMSO (up to 40 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $75.00
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  • Sorafenib | Multi-kinase inhibitor

    CAS:
    475207-59-1
    Catalog Number:
    10-2174
    Activity:
    Inhibitor of Raf-1 and other kinases
    Alternate Names:
    BAY 43-9006
    Chemical Name:
    4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide
    Molecular Weight:
    464.83
    Molecular Formula:
    C21H16ClF3N4O3
    Solubility:
    Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 3 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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