Chemotherapeutics
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Binimetinib | MEK1/2 inhibitor
From $39.00CAS:606143-89-9Catalog Number:10-4789Activity:MEK1/2 inhibitorChemical Name:6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamideAlternate Names:ARRY-162; MEK162Molecular Weight:441.23Molecular Formula:C17H15BrF2N4O3Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Bleomycin sulfate | Induces double strand DNA breaks
From $75.00CAS:9041-93-4Catalog Number:10-2623Activity:Fibrosis-inducing agentSource:From Streptomyces verticillusMolecular Weight:1512.62Molecular Formula:C55H85N17O25S4Solubility:Soluble in Water (up to 20 mg/ml)Physical Properties:White or off-white solidPurity:Contains a mixture of A2 (~70%) and B2 (~30%) forms
95% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from the date of purchase. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Bortezomib | Proteasome inhibitor
From $60.00CAS:179324-69-7Catalog Number:10-2120Activity:Proteasome inhibitorAlternate Names:MG-341, PS-341Chemical Name:N-(2-Pyrazine)carbonyl-L-phenylalanine-L-leucine boronic acidMolecular Weight:384.25Molecular Formula:C19H25BN4O4Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 35 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Bosutinib | Dual Src/Abl kinase inhibitor
From $40.00CAS:380843-75-4Catalog Number:10-2122Activity:Dual Src/Abl kinase inhibitorChemical Names:4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrileAlternate Name:SKI-606Molecular Weight:530.45Molecular Formula:C26H29Cl2N5O3Solubility:Soluble in DMSO (100 mg/ml); Ethanol (up to 25 mg/ml with warming)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Brigatinib | pan-ALK inhibitor
From $50.00CAS:1197953-54-0Catalog Number:10-5034Activity:pan-ALK inhibitorChemical Names:5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4- pyrimidinediamineAlternate Name:AP26113Molecular Weight:584.02Molecular Formula:C29H39ClN7O2PSolubility:Soluble in DMSO (1 mg/ml with warming)Physical Properties:White to off-white solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
EXPLORE OTHER Cancer
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- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
