Chemotherapeutics

  • Brigatinib | pan-ALK inhibitor

    CAS:
    1197953-54-0
    Catalog Number:
    10-5034
    Activity:
    pan-ALK inhibitor
    Chemical Names:
    5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4- pyrimidinediamine
    Alternate Name:
    AP26113
    Molecular Weight:
    584.02
    Molecular Formula:
    C29H39ClN7O2P
    Solubility:
    Soluble in DMSO (1 mg/ml with warming)
    Physical Properties:
    White to off-white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
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  • Cabozantinib | Met and VEGFR2 inhibitor

    CAS:
    849217-68-1
    Catalog Number:
    10-3231
    Activity:
    Met and VEGFR2 inhibitor
    Chemical Name:
    N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Alternate Names:
    XL-184; BMS-907351; Carbozantinib
    Molecular Weight:
    501.51
    Molecular Formula:
    C28H24FN3O5
    Solubility:
    Soluble in DMSO
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Carfilzomib | Proteasome inhibitor

    CAS:
    868540-17-4
    Catalog Number:
    10-1477
    Activity:
    Proteasome inhibitor
    Alternate Names:
    PR-171
    Chemical Name:
    (αS)-α-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]- L-Phenylalaninamide
    Molecular Weight:
    719.93
    Molecular Formula:
    C40H57N5O7
    Solubility:
    Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $50.00
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  • Cisplatin | Anticancer agent

    CAS:
    15663-27-1
    Catalog Number:
    10-2204
    Activity:
    Anticancer agent
    Chemical Name:
    Cis-Diaminodichloroplatinum
    Alternate Names:
    CDDP; cis-Diamineplatinum(II) dichloride
    Molecular Weight:
    300.05
    Molecular Formula:
    Cl2H4N2Pt
    Solubility:
    Soluble in Water (up to 2.5 mg/ml with warming)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    Elemental Analysis (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water are not stable and must be used within 1 working day. do not store solutions.
    Shipping Code:
    RT
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  • Crizotinib | c-MET and ALK inhibitor

    CAS:
    877399-52-5
    Catalog Number:
    10-2626
    Activity:
    c-MET and ALK inhibitor
    Chemical Name:
    3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
    Alternate Names:
    PF-02341066, PF-1066
    Molecular Weight:
    450.34
    Molecular Formula:
    C21H22Cl2FN5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $80.00
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