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DNA Damage/Repair

  • Lomeguatrib | MGMT inhibitor

    CAS:
    192441-08-0
    Catalog Number:
    10-4017
    Activity:
    MGMT inhibitor
    Chemical Name:
    2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purine
    Alternate Name:
    O6-(4-Bromothenyl)guanine
    Molecular Weight:
    326.17
    Molecular Formula:
    C10H8BrN5O3S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml with warming).
    Physical Properties:
    Off-white or beige solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • LY2603618 | Potent and selective Chk1 inhibitor

    CAS:
    911222-45-2
    Catalog Number:
    10-4123
    Activity:
    Potent and selective Chk1 inhibitor
    Chemical Name:
    N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N’-(5-methyl-2-pyrazinyl)urea
    Alternate Names:
    Rabusertib
    Molecular Weight:
    436.30
    Molecular Formula:
    C18H22BrN5O3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • ME-0328 | PARP3 inhibitor

    CAS:
    1445251-22-8
    Catalog Number:
    10-1484
    Activity:
    PARP3 inhibitor
    Chemical Name:
    3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
    Molecular Weight:
    321.38
    Molecular Formula:
    C19H19N3O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 4 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $70.00
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  • Mirin | Mre11-Rad50-Nbs1 inhibitor

    CAS:
    299953-00-7
    Catalog Number:
    10-1069
    Activity:
    Mre11-Rad50-Nbs1 inhibitor
    Chemical Name:
    5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one
    Molecular Weight:
    220.25
    Molecular Formula:
    C10H8N2O2S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Mitomycin C | DNA crosslinking and damaging agent

    CAS:
    50-07-7
    Catalog Number:
    10-1170
    Activity:
    DNA crosslinking and damaging agent
    Chemical Name:
    Natural fermentation product from Streptomyces sp.
    Molecular Weight:
    334.33
    Molecular Formula:
    C15H18N4O5
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).
    Physical Properties:
    Blue-violet solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.
    Shipping Code:
    RT
    From $55.00
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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