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Drug resistance

  • MTX-531 | Dual EGFR/PI3K inhibitor

    CAS:
    2791417-66-6
    Catalog Number:
    10-4802
    View Product This product has multiple variants. The options may be chosen on the product page

  • Napabucasin | STAT3 inhibitor / Cancer cell stemness inhibitor

    CAS:
    83280-65-3
    Catalog Number:
    10-3442
    Activity:
    STAT3 inhibitor / Cancer cell stemness inhibitor
    Chemical Name:
    2-Acetylnsphtho[2,3-b]furan-4,9-dione
    Alternate Names:
    BBI608
    Molecular Weight:
    240.21
    Molecular Formula:
    C14H8O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $58.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • NGI-1 | Oligosaccharyltransferase (OST) inhibitor

    CAS:
    790702-57-7
    Catalog Number:
    10-4291
    Activity:
    Oligosaccharyltransferase (OST) inhibitor
    Chemical Name:
    5-(Dimethylsulfamoyl)-N-(5-methyl-1,3-thiazol-2-yl)-2-(pyrrolidin-1-yl)benzamide
    Alternate Names:
    ML414
    Molecular Weight:
    394.51
    Molecular Formula:
    C17H22N4O3S2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Nicardipine HCl | L-type Ca channel blocker / MDR inhibitor

    CAS:
    54527-84-3
    Catalog Number:
    10-1201
    Activity:
    L-type Ca channel blocker / MDR inhibitor
    Chemical Name:
    1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid methyl ester hydrochloride
    Molecular Weight:
    515.99
    Molecular Formula:
    C26H29N3O6·HCl
    Solubility:
    Soluble in Ethanol (up to 20 mg/ml) or in Water (up to 5 mg/ml).
    Physical Properties:
    Pale-yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Panobinostat | HDAC inhibitor

    CAS:
    404950-80-7
    Catalog Number:
    10-2157
    Activity:
    HDAC inhibitor
    Alternate Names:
    LBH-589
    Chemical Name:
    (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
    Molecular Weight:
    349.44
    Molecular Formula:
    C21H23N3O2
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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