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Epigenetics

  • SGC-iMLLT | MLLT1/3 YEATS domain inhibitor

    CAS:
    2255338-25-9
    Catalog Number:
    10-4046
    Activity:
    MLLT1/3 YEATS domain inhibitor
    Chemical Names:
    (S)-1-Methyl-N-(2-((2-methylpyrrolidin-1-yl)methyl)-1H-benzo[d]imidazole-5-yl)-1H-indazole-5-carboxamide
    Molecular Weight:
    388.48
    Molecular Formula:
    C22H24N6O
    Solubility:
    Soluble in DMSO (at least 50 mg/ml)
    Physical Properties:
    Off-white to beige solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • SGI-1027 | DNA methyl transferase inhibitor

    CAS:
    1020149-73-8
    Catalog Number:
    10-5488
    Activity:
    DNA methyl transferase inhibitor
    Chemical Names:

    N-[4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)benzamide

    Molecular Weight:
    461.52
    Molecular Formula:
    C27H23N7O
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • SP2509 | LSD1 inhibitor

    CAS:
    1423715-09-6
    Catalog Number:
    10-4019
    Activity:
    LSD1 inhibitor
    Chemical Name:
    (E)-N’-(1-(5-Chloro-2-hydroxyphenyl)ethylidene)-3-(morpholinosulfonyl)benzohydrazide
    Molecular Weight:
    437.90
    Molecular Formula:
    C19H20ClN3O5S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Tazemetostat | EZH2 inhibitor

    CAS:
    1403254-99-8
    Catalog Number:
    10-4032
    Activity:
    EZH2 inhibitor
    Chemical Name:
    N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4’-(morpholinomethyl)-[1,1’-biphenyl]-3-carboxamide
    Alternate Name:
    EPZ-6438
    Molecular Weight:
    572.75
    Molecular Formula:
    C34H44N4O4
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • TC-E 5003 | Arginine methyltransferase 1 (PRMT1) inhibitor

    CAS:
    17328-16-4
    Catalog Number:
    10-1499
    Activity:
    Arginine methyl transferase 1 (PRMT1) inhibitor
    Chemical Name:
    N,N’-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide)
    Molecular Weight:
    401.26
    Molecular Formula:
    C16H14Cl2N2O4S
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    Brown solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
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