Kinases Archives | Page 29 of 30

Volasertib | Potent and selective inhibitor of Polo-like kinase 1

CAS:

755038-65-4

Catalog Number:

10-4818

Activity:

Potent and selective inhibitor of Polo-like kinase 1

Chemical Name:

N-[4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-4-[[(7R)-7-ethyl-5-methyl-6-oxo-8-propan-2-yl-7H-pteridin-2-yl]amino]-3-methoxybenzamide

Alternate Name:

BI 6727

Molecular Weight:

618.82

Molecular Formula:

C₃₄H₅₀N₈O₃

Solubility:

Soluble in DMSO (up to at least 25 mg/ml).

Physical Properties:

Off-white solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $80.00
Select options
WHI-P131 | JAK3 inhibitor

CAS:

202475-60-3

Catalog Number:

10-1190

Activity:

JAK3 inhibitor

Alternate Names:

JANEX-1

Chemical Name:

4-[(4′-Hydroxyphenyl)amino]-6,7-dimethoxyquinazoline

Molecular Weight:

333.78

Molecular Formula:

C₁₆H₁₅N₃O₃·HCl

Solubility:

Soluble in DMSO (up to 50 mg/ml).

Physical Properties:

Yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $60.00
Select options
WNK463 | pan-WNK kinase inhibitor

CAS:

2012607-27-9

Catalog Number:

10-4109

Activity:

pan-WNK kinase inhibitor

Chemical Names:

N-tert-Butyl-3-[1-[5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]pyridine-2-yl]piperidin-4-yl]imidazole-4-carboxamide

Molecular Weight:

463.47

Molecular Formula:

C₂₁H₂₄F₃N₇O₂

Solubility:

Soluble in DMSO (>25 mg/ml)

Physical Properties:

White solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $90.00
Select options
ZM-336372 | c-Raf inhibitor

CAS:

208260-29-1

Catalog Number:

10-1030

Activity:

c-Raf inhibitor

Chemical Name:

3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide

Molecular Weight:

389.46

Molecular Formula:

C₂₃H₂₃N₃O₃

Solubility:

Soluble in DMSO (up to 50 mg/ml).

Physical Properties:

Off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $60.00
Select options
ZM-447439 | Aurora B kinase inhibitor

CAS:

331771-20-1

Catalog Number:

10-1037

Activity:

Aurora B kinase inhibitor

Chemical Name:

N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide

Molecular Weight:

513.59

Molecular Formula:

C₂₉H₃₁N₅O₄

Solubility:

Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).

Physical Properties:

White solid

Purity:

98% by TLC

Storage Temperature:

RT

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $52.00
Select options

Kinases

Volasertib | Potent and selective inhibitor of Polo-like kinase 1

WHI-P131 | JAK3 inhibitor

WNK463 | pan-WNK kinase inhibitor

ZM-336372 | c-Raf inhibitor

ZM-447439 | Aurora B kinase inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

Volasertib | Potent and selective inhibitor of Polo-like kinase 1

WHI-P131 | JAK3 inhibitor

WNK463 | pan-WNK kinase inhibitor

ZM-336372 | c-Raf inhibitor

ZM-447439 | Aurora B kinase inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21