Kinases
-
Alectinib | Potent and selective ALK inhibitor
From $60.00CAS:1256580-46-7Catalog Number:10-4793Activity:Potent and selective ALK inhibitorChemical Name:9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrileAlternate Name:CH5424802Molecular Weight:482.62Molecular Formula:C30H34N4O2Solubility:Soluble in DMSO (up to 5 mg/ml with warming).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.Shipping Code:RT -
Alisertib | Potent and selective inhibitor of Aurora A / Destabilizes Myc
From $60.00CAS:1028486-01-2Catalog Number:10-4124Activity:Potent and selective inhibitor of Aurora A / Destabilizes MycChemical Name:4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoic acidAlternate Names:MLN8237Molecular Weight:518.92Molecular Formula:C27H20ClFN4O4Solubility:Soluble in DMSO (up to 5 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Apigenin | Protein kinase inhibitor
From $36.00CAS:520-36-5Catalog Number:10-1242Activity:Protein kinase inhibitorAlternate Names:4,5,7-TrihydroxyflavoneChemical Name:5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-oneMolecular Weight:270.24Molecular Formula:C15H10O5Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Pale yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Axitinib | VEGFR kinase inhibitor
From $40.00CAS:319460-85-0Catalog Number:10-2118Activity:VEGFR kinase inhibitorChemical Name:N-Methyl-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamideMolecular Weight:386.47Molecular Formula:C22H18N4OSSolubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
AZ3146 | Mps1 kinase inhibitor
From $60.00CAS:1124329-14-1Catalog Number:10-4778Activity:Mps1 kinase inhibitorChemical Name:9-Cyclopentyl-2-[2-methoxy-4-(1-methylpiperidine-4-yl)oxyanilino]-7-methylpurin-8-oneMolecular Weight:452.56Molecular Formula:C24H32N6O3S2Solubility:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to at least 25 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
