Programmed cell death
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SM-164 | Smac mimetic
From $190.00CAS:957135-43-2Catalog Number:10-5464Activity:Smac mimeticChemical Names:(3S,3′S,6S,6′S,10aS,10′aS)-N,N′-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamideMolecular Weight:1121.45Molecular Formula:C62H84N14O6Solubility:Soluble in DMSO (50 mg/ml)Physical Properties:White to pale-yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Sorafenib | Multi-kinase inhibitor
From $40.00CAS:284461-73-0Catalog Number:10-2174Activity:Inhibitor of Raf-1 and other kinasesAlternate Names:BAY 43-9006Chemical Name:4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamideMolecular Weight:464.83Molecular Formula:C21H16ClF3N4O3Solubility:Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 3 mg/ml).Physical Properties:Off-white solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
SP2509 | LSD1 inhibitor
From $75.00CAS:1423715-09-6Catalog Number:10-4019Activity:LSD1 inhibitorChemical Name:(E)-N’-(1-(5-Chloro-2-hydroxyphenyl)ethylidene)-3-(morpholinosulfonyl)benzohydrazideMolecular Weight:437.90Molecular Formula:C19H20ClN3O5SSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Spautin-1 | Inhibits autophagy by inhibiting USP 10 and 13
From $65.00CAS:1262888-28-7Catalog Number:10-1367Activity:Inhibits autophagy by inhibiting USP 10 and 13Chemical Name:6-Fluoro-N[(4-fluorophenyl)methyl]-4-quinazolinamineMolecular Weight:271.27Molecular Formula:C15H11F2N3Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).Physical Properties:Tan solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
SR9243 | LXR inverse agonist
From $45.00CAS:1613028-81-1Catalog Number:10-4579Activity:LXR inverse agonistChemical Name:N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3Õ-(methylsulfonyl)[1,1Õ-biphenyl]-4-yl]methyl]-benzenesulfonamideMolecular Weight:626.62Molecular Formula:C31H32BrNO4S2Solubility:Soluble in DMSO (greater than 25 mg/ml)Physical Properties:White solidPurity:>98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
