Cyclin/CDK

  • Abemaciclib | Potent and selective CDK 4/6 inhibitor

    CAS:
    1231930-82-7
    Catalog Number:
    10-4833
    Activity:
    Potent and selective CDK 4/6 inhibitor
    Chemical Name:
    N-[5-[(4-Ethylpiperazin-1-yl)methyl]pyridine-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine methanesulfonic acid salt
    Alternate Name:
    LY2835219 mesylate
    Molecular Weight:
    602.70
    Molecular Formula:
    C27H32F2N8 ∙ CH3SO3H
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Alsterpaullone | GSK-3ß inhibitor

    CAS:
    237430-03-4
    Catalog Number:
    10-1397
    Activity:
    GSK3β inhibitor, CDK5/p25 inhibitor
    Chemical Name:
    9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5)-one
    Molecular Weight:
    293.28
    Molecular Formula:
    C16H11N3O3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    Brown solid
    Purity:
    96% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $56.00
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  • BML-259 | CDK5/p25 inhibitor

    CAS:
    267654-00-2
    Catalog Number:
    10-1025
    Activity:
    CDK5/p25 inhibitor
    Chemical Name:
    N-(5-isopropyl-thiazol-2-yl)phenylacetamide
    Molecular Weight:
    260.36
    Molecular Formula:
    C14H16N2OS
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    white solid
    Purity:
    98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • Fascaplysin | CDK4 inhibitor

    CAS:
    114719-57-2
    Catalog Number:
    10-1517
    Activity:
    CDK4 inhibitor
    Chemical Name:
    12,13-Dihydro-13-oxopyrido[1,2-a:3,4-b’]diindol-5-ium chloride
    Molecular Weight:
    306.75
    Molecular Formula:
    C18H11ClN2O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 2 mg/ml)
    Physical Properties:
    Dark red-brown solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Flavopiridol HCl | CDK inhibitor

    CAS:
    131740-09-5
    Catalog Number:
    10-3063
    Activity:
    CDK inhibitor
    Chemical Name:
    3-(3-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, hydrochloride
    Alternate Names:
    L 86-8275; Alvocidib; NSC-649890
    Molecular Weight:
    438.30
    Molecular Formula:
    C21H20ClNO5 &bul; HCl
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Water (up to 40 mg/ml).
    Physical Properties:
    Light yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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