Inhibitors
-
Pemetrexed 2Na | Multitargeted antifolate
From $70.00CAS:357166-29-1Catalog Number:10-2162Activity:Multi-targeted antifolateChemical Name:N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, disodium saltMolecular Weight:597.49Molecular Formula:C20H19N5O6 • 2Na • 7H2OSolubility:Soluble in Water (up to 100 mg/ml).Physical Properties:White solidPurity:98% by TLC and HPLC
NMR (Conforms)Storage Temperature:-20° (des.)Stability:Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 31month.Shipping Code:RT -
PLX4032 | BRAF inhibitor
From $40.00CAS:918504-65-1Catalog Number:10-2928Activity:BRAF inhibitorChemical Name:N-[3-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamideAlternate Names:Vemurafenib, R7204, Ro 51-85426Molecular Weight:489.92Molecular Formula:C23H18ClF2N3O3SSolubility:Soluble in DMSO (up to 100 mg/ml)Physical Properties:White or off-white solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Scriptaid | HDAC inhibitor
From $75.00CAS:287383-59-9Catalog Number:10-2712Activity:HDAC inhibitorChemical Name:6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-N-hydroxyhexanamideAlternate Name:Scriptide; GCK1026Molecular Weight:326.35Molecular Formula:C18H18N2O4Solubility:Soluble in DMSO (up to 4 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.Shipping Code:RT -
Simvastatin | HMG-CoA reductase inhibitor
From $50.00CAS:79902-63-9Catalog Number:10-1018Activity:HMG-CoA reductase inhibitorAlternate Names:MevinolinChemical Name:2,2-Dimethyl-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acidMolecular Weight:418.58Molecular Formula:C25H38O5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
SKPin C1 | Ubiquitin ligase E3 SCF-Skp2 inhibitor
From $70.00CAS:432001-69-9Catalog Number:10-1441Activity:Ubiquitin ligase E3 SCF-Skp2 inhibitorChemical Names:2-[4-Bromo-2-[[4-oxo-3-(3-pyridinyl¬methyl)-2-thioxo-5-thiazolidinylidene]methyl]-phenoxy]acetic acidMolecular Weight:465.34Molecular Formula:C18H13BrN2O4S2Solubility:Soluble in DMSO (15 mg/ml with warming)Physical Properties:Yellow solidPurity:98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month.Shipping Code:RT
