Programmed cell death

  • GSK872 | Necroptosis inhibitor / RIP3 inhibitor

    CAS:
    1346546-69-7
    Catalog Number:
    10-4861
    Activity:
    Necroptosis inhibitor / RIP3 inhibitor
    Chemical Name:
    N-(6-Propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine
    Alternate Names:
    GSK2399872A
    Molecular Weight:
    383.49
    Molecular Formula:
    C19H17N3O2S2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-White or pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Hydroxychloroquine sulfate | Autophagy inhibitor

    CAS:
    747-36-4
    Catalog Number:
    10-1379
    Activity:
    Antimalarial/Autophagy inhibitor
    Chemical Names:
    7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinolone sulfate
    Molecular Weight:
    433.96
    Molecular Formula:
    C18H26ClN3O·H2SO4
    Solubility:
    Soluble in Water (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • icFSP1 | Ferroptosis suppressor protein (FSP1) inhibitor

    CAS:
    1115910-36-5
    Catalog Number:
    10-5735
    View Product This product has multiple variants. The options may be chosen on the product page
  • Irinotecan HCl | Topoisomerase I inhibitor

    CAS:
    136572-09-3
    Catalog Number:
    10-2146
    Activity:
    Topoisomerase I inhibitor
    Chemical Name:
    (S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4′-bipiperidine]-1′-carboxylate hydrochloride
    Molecular Weight:
    677.2
    Molecular Formula:
    C33H38N4O6 HCl 3H2O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), in Water (up to 4 mg/ml) or in Ethanol (up to 4 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • K252A | Kinase inhibitor (pan-specific)

    CAS:
    99533-80-9
    Catalog Number:
    10-2080
    Activity:
    Kinase inhibitor (pan-specific)
    Molecular Weight:
    467.49
    Molecular Formula:
    C27H21N3O5
    Solubility:
    Soluble in DMSO (up to 100 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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