UPR
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Importazole | Blocks importin-ß-mediated nuclear import
From $50.00CAS:662163-81-7Catalog Number:10-1412Activity:Blocks importin-β-mediated nuclear importAlternate Names:IPZChemical Name:N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amineMolecular Weight:318.43Molecular Formula:C20H22N4Solubility:Soluble in DMSO (up to 10 mg/ml).Physical Properties:Off-white solidPurity:97% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
ISRIB | Integrated stress response inhibitor
From $60.00CAS:159403-47-8Catalog Number:10-1539Activity:Integrated stress response inhibitorChemical Name:N.N’-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamideAlternate Names:trans-ISRIBMolecular Weight:451.34Molecular Formula:C22H24Cl2N2O4Solubility:Soluble in DMSO (up to 5 mg/ml with warming)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Metolazone | UPR activator and longevity inducer
From $50.00CAS:17560-51-9Catalog Number:10-5417Activity:UPR activator and longevity inducerChemical Name:7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
Molecular Weight:365.83Molecular Formula:C16H16ClN3O3SSolubility:Soluble in DMSO (up to 36 mg/ml)Physical Properties:White solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years as supplied. Solutions in DMSO may be stored desiccated at -20°C for up to 2 months.Shipping Code:RT -
STF-083010 | IRE1 inhibitor
From $50.00CAS:307543-71-1Catalog Number:10-1510Activity:Inhibits IRE1Chemical Name:N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamideMolecular Weight:317.39Molecular Formula:C15H11NO3S2Solubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
