Cancer immunotherapy
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Defactinib | Potent FAK inhibitor
From $65.00CAS:1073154-85-4Catalog Number:10-4828Activity:Potent FAK inhibitorChemical Name:N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamideMolecular Weight:510.50Molecular Formula:C20H21F3N8O3SSolubility:Soluble in DMSO (up to at least 25mg/ml)Physical Properties:White solidPurity:98% by HPLCNMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Duvelisib | PI3Kdelta/gamma inhibitor
From $65.00CAS:1201438-56-3Catalog Number:10-4788Activity:PI3Kδ/γ inhibitor/Cancer immunotherapy enhancerChemical Name:8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-oneAlternative Name:IPI-145Molecular Weight:416.87Molecular Formula:C22H17ClN6OSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Epacadostat | IDO1 inhibitor
From $45.00CAS:1204669-58-8Catalog Number:10-4499Activity:IDO1 inhibitor/ Cancer immunotherapy enhancerChemical Name:N-(3-Bromo-4-fluorophenyl)-N’-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamideAlternate Name:INCB024360Molecular Weight:438.23Molecular Formula:C11H13BrFN7O4SSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic
From $45.00CAS:700874-72-2Catalog Number:10-4110Activity:Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeuticChemical Name:4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamideAlternate Names:LY2157299Molecular Weight:369.43Molecular Formula:C22H19N5OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Ganetespib | HSP90 inhibitor
From $60.00CAS:888216-25-9Catalog Number:10-4474Activity:HSP90 inhibitorChemical Name:3-(2,4-Dihydroxy-5-propan-2-ylphenyl)-4-(1-methylindol-5-yl)-1H-1,2,4-triazol-5-one;
Molecular Weight:364.40Molecular Formula:C20H20N4O3Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:>98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
