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Cancer immunotherapy

  • R428 Chemical structure

    R428 | Potent and selective AXL inhibitor

    CAS:
    1037624-75-1
    Catalog Number:
    10-4676
    Activity:
    Potent and selective AXL inhibitor
    Chemical Name:
    1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine
    Alternate Names:
    Bemcentinib; BGB324
    Molecular Weight:
    506.64
    Molecular Formula:
    C30H34N8
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Sitravatinib | Multikinase inhibitor / Immuno-oncology agent

    CAS:
    1123837-84-2
    Catalog Number:
    10-4826
    Activity:
    Multikinase inhibitor / Immuno-oncology agent
    Chemical Name:
    1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Alternate Names:
    MGCD516
    Molecular Weight:
    629.68
    Molecular Formula:
    C33H29N5O4S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • SLC-0111 | Carbonic anhydrase IX/XII inhibitor

    CAS:
    178606-66-1
    Catalog Number:
    10-4185
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  • SR0987 | RORγt agonist

    CAS:
    303126-97-8
    Catalog Number:
    10-4008
    Activity:
    RORγt Agonist/Cancer immunotherapy enhancer
    Chemical Name:
    2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide
    Molecular Weight:
    397.70
    Molecular Formula:
    C16H10F6NO2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) and Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • STC-15 chemical structure

    STC-15 | METTL3 inhibitor

    CAS:
    2648257-56-9
    Catalog Number:
    10-4874
    View Product This product has multiple variants. The options may be chosen on the product page
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