Cancer immunotherapy
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R428 | Potent and selective AXL inhibitor
From $75.00CAS:1037624-75-1Catalog Number:10-4676Activity:Potent and selective AXL inhibitorChemical Name:1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamineAlternate Names:Bemcentinib; BGB324Molecular Weight:506.64Molecular Formula:C30H34N8Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Sitravatinib | Multikinase inhibitor / Immuno-oncology agent
From $50.00CAS:1123837-84-2Catalog Number:10-4826Activity:Multikinase inhibitor / Immuno-oncology agentChemical Name:1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideAlternate Names:MGCD516Molecular Weight:629.68Molecular Formula:C33H29N5O4SSolubility:Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
SR0987 |RORγt agonist
From $65.00CAS:303126-97-8Catalog Number:10-4008Activity:RORγt Agonist/Cancer immunotherapy enhancerChemical Name:2-Chloro-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamideMolecular Weight:397.70Molecular Formula:C16H10F6NO2Solubility:Soluble in DMSO (up to at least 25 mg/ml) and Ethanol (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Trametinib | MEK inhibitor
From $40.00CAS:871700-17-3Catalog Number:10-4759Activity:MEK inhibitorChemical Name:N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamideAlternate Names:GSK1120212Molecular Weight:615.39Molecular Formula:C26H23FIN5O4Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
URMC-099 | MLK3 inhibitor
From $55.00CAS:1229582-33-5Catalog Number:10-4012Activity:MLK3 inhibitorChemical Names:3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridineMolecular Weight:421.54Molecular Formula:C27H27N5Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
