Cancer immunotherapy

  • NLG919 | IDO pathway inhibitor

    CAS:
    1402836-58-1
    Catalog Number:
    10-4564
    Activity:
    IDO pathway inhibitor
    Chemical Names:
    1-Cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol
    Molecular Weight:
    282.39
    Molecular Formula:
    C18H22N2O
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • PD-1/PD-L1 Inhibitor 1

    CAS:
    1675201-83-8
    Catalog Number:
    10-4901
    Activity:
    PD-1/PD-L1 inhibitor
    Chemical Name:
    (2S)-1-[[2,6-Dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]pipieridine-2-carboxylic acid
    Alternate Name:
    BMS-3
    Molecular Weight:
    475.59
    Molecular Formula:
    C29H33N2O5
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $95.00
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  • Pexidartinib | CSF1R inhibitor

    CAS:
    1029044-16-3
    Catalog Number:
    10-4829
    Activity:
    CSF1R inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    5-[(5-Chloro-1H-pyrrolo[2,3.b]pyridine-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
    Alternate Names:
    PLX3397
    Molecular Weight:
    417.81
    Molecular Formula:
    C20H15ClF3N5
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
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  • PF-06840003 | IDO1 inhibitor

    CAS:
    198474-05-4
    Catalog Number:
    10-4498
    Activity:
    IDO1 inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
    Alternate Name:
    EOS200271
    Molecular Weight:
    232.21
    Molecular Formula:
    C12H9FN2O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • PF-4136309 | CCR2 antagonist

    CAS:
    1341224-83-6
    Catalog Number:
    10-4261
    Activity:
    CCR2 antagonist
    Chemical Name:
    N-[2-[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
    Alternate Name:
    INCB8761
    Molecular Weight:
    568.60
    Molecular Formula:
    C29H31F3N6O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page
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