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Cancer immunotherapy

  • IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent

    CAS:
    1693758-51-8
    Catalog Number:
    10-4827
    Activity:
    Selective PI3K-gamma inhibitor / Immuno-oncology agent
    Chemical Name:
    (S)-2-Amino-N-[1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide; Eganelisib
    Molecular Weight:
    528.58
    Molecular Formula:
    C30H24N8O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • JPH203 | LAT1 inhibitor

    CAS:
    1597402-27-1
    Catalog Number:
    10-4464
    Activity:
    LAT1 inhibitor
    Chemical Names:
    (2S)-2-Amino-3-[4-[(5-amino-2-phenyl-1,3-benzoxazol-7-yl)methoxy]-3,5-dichlorophenyl]propanoic acid dihydrochloride
    Alternate Name:
    KYT-0353; Nanvuralant
    Molecular Weight:
    545.24
    Molecular Formula:
    C23H19Cl2N3O4·2HCl
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Pale orange/yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $95.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • KIRA6 | IRE1α inhibitor

    CAS:
    1589527-65-0
    Catalog Number:
    10-4886
    View Product This product has multiple variants. The options may be chosen on the product page

  • Linrodostat | IDO1 inhibitor

    CAS:
    1923833-60-6
    Catalog Number:
    10-4473
    View Product This product has multiple variants. The options may be chosen on the product page

  • Luminespib | HSP90 inhibitor

    CAS:
    747412-49-3
    Catalog Number:
    10-4672
    Activity:
    HSP90 inhibitor
    Chemical Names:
    5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide
    Alternate Name:
    NVP-AUY922; VER-52296
    Molecular Weight:
    465.54
    Molecular Formula:
    C26H31N3O5
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page
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