Immunosuppressants

  • Helenalin | NFkB inhibitor

    CAS:
    6754-13-8
    Catalog Number:
    10-2783
    Activity:
    NFκB inhibitor
    Chemical Name:
    Natural sesquiterpenoid from Arnica species
    Molecular Weight:
    262.31
    Molecular Formula:
    C15H18O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    $238.00
  • IQ-1S | JNK3 inhibitor

    CAS:
    1421610-21-0
    Catalog Number:
    10-1513
    Activity:
    JNK3 inhibitor
    Chemical Name:
    11H-Indeno[1,2-b]quinoxaline-11-one oxime, sodium salt
    Molecular Weight:
    269.23
    Molecular Formula:
    C15H8N3O • Na
    Solubility:
    Soluble in DMSO (up to 15 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
  • Kynurenine (L) | Endogenous AhR agonist

    CAS:
    2922-83-0
    Catalog Number:
    10-2666
    Activity:
    Endogenous AhR agonist
    Chemical Name:
    β-Anthraniloyl-L-alanine; L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
    Molecular Weight:
    208.22
    Molecular Formula:
    C10H12N2O3
    Solubility:
    Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $38.00
  • Leflunomide | Immunosuppressant

    CAS:
    75706-12-6
    Catalog Number:
    10-2369
    Activity:
    Immunosuppressant
    Alternate Names:
    RS-34821
    Chemical Name:
    5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide
    Molecular Weight:
    270.21
    Molecular Formula:
    C12H9F3N2O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
  • Methotrexate | Dihydrofolate reductase inhibitor

    CAS:
    133073-73-1
    Catalog Number:
    10-1260
    Activity:
    Dihydrofolate reductase inhibitor
    Chemical Names:
    N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid; Amethopterin; CL-14377; NSC740
    Molecular Weight:
    683.63
    Molecular Formula:
    C20H22N8O5·XH2O
    Solubility:
    Soluble in DMSO (45 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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