Kinases
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Galunisertib | Potent TGFB receptor 1 inhibitor / Cancer immunotherapeutic
From $45.00CAS:700874-72-2Catalog Number:10-4110Activity:Potent TGF-β receptor 1 inhibitor / Cancer immunotherapeuticChemical Name:4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamideAlternate Names:LY2157299Molecular Weight:369.43Molecular Formula:C22H19N5OSolubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
GSK2982772 | RIP1 inhibitor
From $95.00CAS:1622848-92-3Catalog Number:10-4792Activity:RIP1 kinase inhibitorChemical Names:(S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2,4-traizole-3-carboxamide; GSK772Molecular Weight:377.40Molecular Formula:C20H19N5O3Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
GSK8612 | Highly selective TBK1 inhibitor
From $65.00CAS:2361659-62-1Catalog Number:10-4693Activity:Highly selective TBK1 inhibitorChemical Names:4-[[[5-Bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamideMolecular Weight:520.33Molecular Formula:C17H17BrF3N7O2SSolubility:Soluble in DMSO (20 mg/ml)Physical Properties:Beige solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Ibrutinib | BTK inhibitor
From $40.00CAS:936563-96-1Catalog Number:10-4757Alternate Name:PCI-32765Activity:BTK inhibitor/Cancer immunotherapy enhancerChemical Name:1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-oneMolecular Weight:440.51Molecular Formula:C25H24N6O2Solubility:Soluble in DMSO ( up to at least 25 mg/ml)Physical Properties:White or off-white solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
