Kinases

  • GSK2982772 | RIP1 inhibitor

    CAS:
    1622848-92-3
    Catalog Number:
    10-4792
    Activity:
    RIP1 kinase inhibitor
    Chemical Names:
    (S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2,4-traizole-3-carboxamide; GSK772
    Molecular Weight:
    377.40
    Molecular Formula:
    C20H19N5O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $95.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • GSK8612 | Highly selective TBK1 inhibitor

    CAS:
    2361659-62-1
    Catalog Number:
    10-4693
    Activity:
    Highly selective TBK1 inhibitor
    Chemical Names:
    4-[[[5-Bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
    Molecular Weight:
    520.33
    Molecular Formula:
    C17H17BrF3N7O2S
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    Beige solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Ibrutinib | BTK inhibitor

    CAS:
    936563-96-1
    Catalog Number:
    10-4757
    Alternate Name:
    PCI-32765
    Activity:
    BTK inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
    Molecular Weight:
    440.51
    Molecular Formula:
    C25H24N6O2
    Solubility:
    Soluble in DMSO ( up to at least 25 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Idelalisib | Selective PI3Kδ Inhibitor

    CAS:
    870281-82-6
    Catalog Number:
    10-4820
    Activity:
    Selective PI3Kδ Inhibitor
    Chemical Name:
    5-Fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
    Alternate Names:
    CAL-101
    Molecular Weight:
    415.43
    Molecular Formula:
    C21H18FN7O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Intelliscreen™ Highly-Selective Kinase Inhibitor Library

    Catalog Number:
    10-7001
    Description:
    166 highly selective inhibitors of various kinases.
    Solubility:
    DMSO
    Supplied As:
    DSMO solution @ 10mM
    Storage Temperature:
    -80°C
    Stability:
    Stable for up to 1 year when stored as supplied @ -80°C
    Price:
    $3 700.00
    $3,700.00
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