Neurodegeneration

  • Rotenone | Mitochondrial Complex I Inhibitor

    CAS:
    83-79-4
    Catalog Number:
    10-2277
    Activity:
    Mitochondrial Complex I Inhibitor
    Chemical Names:
    (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one
    Alternate Name:
    NSC-26285; Nicouline
    Molecular Weight:
    394.42
    Molecular Formula:
    C23H22O6
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room Temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $48.00
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  • Rottlerin | PKCδ inhibitor

    CAS:
    82-08-6
    Catalog Number:
    10-1341
    Activity:
    PKCδ inhibitor
    Chemical Name:
    3′-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2′,4′,6′-trihydroxy-5′-methylacetophenone
    Molecular Weight:
    516.65
    Molecular Formula:
    C30H28O8
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    Brown solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Rufinamide | Anticonvulsant / Improves cognition

    CAS:
    106308-44-5
    Catalog Number:
    10-4275
    Activity:
    Anticonvulsant / Improves cognition
    Chemical Name:
    1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
    Molecular Weight:
    238.19
    Molecular Formula:
    C10H8F2N4O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $25.00
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  • SA4503 | Potent and selective sigma-1 agonist

    CAS:
    165377-44-6
    Catalog Number:
    10-4219
    Activity:
    Potent and selective sigma-1 agonist
    Chemical Name:
    1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride
    Alternate Name:
    Cutamesine
    Molecular Weight:
    441.43
    Molecular Formula:
    C23H32N2O2 • 2HCl
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Water (up to at least 25 mg/ml)..
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Safinamide | MAO-B inhibitor; Parkinson’s therapeutic

    CAS:
    133865-89-1
    Catalog Number:
    10-2924
    Activity:
    MAO-B inhibitor; Parkinson’s therapeutic
    Chemical Name:
    (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide
    Alternate Name:
    FCE-26743; PNU-151774E; NW-1015
    Molecular Weight:
    302.34
    Molecular Formula:
    C17H19FN2O2
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $48.00
    View Product This product has multiple variants. The options may be chosen on the product page
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