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Abemaciclib | Potent and selective CDK 4/6 inhibitor
From $50.00CAS:1231930-82-7Catalog Number:10-4833Activity:Potent and selective CDK 4/6 inhibitorChemical Name:N-[5-[(4-Ethylpiperazin-1-yl)methyl]pyridine-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine methanesulfonic acid saltAlternate Name:LY2835219 mesylateMolecular Weight:602.70Molecular Formula:C27H32F2N8 ∙ CH3SO3HSolubility:Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml).Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
ABT-263 | Bcl-2 family inhibitor; Senolytic agent
From $60.00CAS:923564-51-6Catalog Number:10-3141Activity:Bcl-2 family inhibitor; Senolytic agentChemical Name:4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)- 3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]-benzamideAlternate Name:NavitoclaxMolecular Weight:974.61Molecular Formula:C47H55ClF3N5O6S3Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
ABT-418 HCl | Nicotinic acetylcholine receptor agonist/cognition enhancer
From $90.00CAS:147388-83-8Catalog Number:10-1470Activity:Nicotinic acetylcholine receptor agonist; cognition enhancerChemical Name:3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole hydrochlorideMolecular Weight:202.68Molecular Formula:C9H14N2O HClSolubility:Soluble in Water (up to 15 mg/ml)Physical Properties:Tan solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
ABT-737 | Senolytic Bcl2 inhibitor
From $80.00CAS:852808-04-9Catalog Number:10-3661Activity:Senolytic Bcl inhibitorChemical Names:4-[4-[(4′-Chloro[1,1′-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]-benzamideMolecular Weight:813.43Molecular Formula:C42H45ClN6O5S2Solubility:Soluble in DMSO (5 mg/ml)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
