May 28, 2026
FOCUS on Drug Repurposing. Montelukast is a cysteinyl leukotriene receptor (CysLTR1) antagonist currently in use for asthma. In a paper just out in Nature Cancer, a […]
February 19, 2026
FOCUS on new drug approvals. On February 12th the FDA granted approval for Acrotech Biopharma’s Difamilast (Adquey) for mild to moderate atopic dermatitis. The approval marks […]
February 5, 2026
FOCUS On Kinase Inhibitors. The FDA recently approved its 100th kinase inhibitor, marking a major milestone in precision medicine since its first kinase inhibitor approval (Imatinib) […]
November 14, 2025
FOCUS on New Drug Approvals. The FDA has approved Boehringer Ingelheim’s Nerandomilast (Jascayd, BI-101555) for patients with idiopathic pulmonary fibrosis (IPF) a rare, serious, and progressive […]
July 1, 2025
FOCUS on Stem Cell Rejuvenation. In the current issue of Cell Stem Cell, a group from Stanford reported that an endogenous eicosanoid, prostaglandin E2 (PGE2) reversed […]
June 12, 2025
FOCUS on Drug MOA. The mechanism of action of acetaminophen has been determined by a group led by Avi Priel at the Hebrew University, Jerusalem, and […]
February 26, 2025
FOCUS on Bioactive Natural Products. In a February Nature Communications paper, Wang and coworkers showed that a sesquiterpenoid found abundantly in ginger, known as furanodienone, alleviated […]
August 25, 2022
In a recent paper in Cell Research, Li and coworkers explored the nuclear function of RIPK1 and demonstrated that RIPK1 phosphorylates a key component of the […]