July 16, 2026
FOCUS on muscle regeneration. A group at Wash. U. recently reported on a compound designated BE2012 in J. Med. Chem. BE2012 was shown to be a […]
June 25, 2026
Focus Biomolecules will be exhibiting at the annual meeting of the International Society for Stem Cell Research in Montreal, July 8 – 10. Stop by our […]
April 16, 2026
FOCUS on Mitochondrial Disease. Leigh syndrome (LS) is a mitochondrial disease characterized by neurodevelopmental regression and muscle weakness with early death following metabolic crises. In a […]
July 1, 2025
FOCUS on Stem Cell Rejuvenation. In the current issue of Cell Stem Cell, a group from Stanford reported that an endogenous eicosanoid, prostaglandin E2 (PGE2) reversed […]
March 30, 2023
New Product Focus: Chroman 1 is an important new small molecule tool for the generation and maintenance of stem cells. An extremely potent (1 pM) inhibitor […]
September 1, 2022
Chroman 1 is an important new small molecule tool for the generation and maintenance of stem cells. An extremely potent (1 pM) inhibitor of Rho kinase […]
June 22, 2022
Kumar et al. and Zijlmans et al. have published in Nature Cell Biology that Polycomb repressive complex 2 (PRC2) epigenetically reduces lineage potential of hESCs. They […]
May 12, 2022
In Nature Communications, Zhang et al. show that DJ001, a selective allosteric inhibitor of protein tyrosine phosphatase sigma (PTPσ), promotes hematopoietic stem cell (HSC) regeneration. Treatment […]
April 27, 2022
CHIR-99021 is another popular tool for stem cell maintenance which increases cell survival and proliferation. It is a GSK3β inhibitor, and Komiya et al. used CHIR-99021 […]