Approved Drugs
Showing 157–168 of 192 results
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Approved Drugs
Rufinamide | Anticonvulsant / Improves cognition
Rufinamide (106308-44-5) is a clinically useful anticonvulsant medication.1 Its mechanism of action is believed to be inhibition of Nav1.1 and Nav1...$25.00 – $85.00 Select options -
Approved Drugs
Safinamide | MAO-B inhibitor; Parkinson’s therapeutic
Safinamide (133865-89-1) is a selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity o...$48.00 – $220.00 Select options -
Approved Drugs
SAHA | HDAC inhibitor
SAHA (149647-78-9) is a potent and selective histone deacetylase inhibitor. Induces apoptosis in a variety of tumor cell lines. SAHA synergizes wit...$35.00 – $95.00 Select options -
New Products
Saxagliptin HCl | DPP-IV inhibitor
Saxagliptin (709031-78-7) is a clinically useful DPPIV inhibitor for the treatment of diabetes.1 Human DPP-IV Ki = 0.6 nM.2 References: Ta...$39.00 – $140.00 Select options -
Approved Drugs
Sildenafil citrate | PDE5 inhibitor
Sildenafil citrate (171599-83-0) is a potent and selective phosphodiesterase (PDE5) inhibitor, IC50=4 nM).1-3 Clinically useful agent for male erec...$36.00 – $90.00 Select options -
Apoptosis
Simvastatin | HMG-CoA reductase inhibitor
Simvastatin (79902-63-9) is a synthetic analog of lovastatin (cat.# 10-1222). Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-...$50.00 – $165.00 Select options -
Approved Drugs
Sivelestat sodium | Leukocyte elastase inhibitor
Sivelestat sodium (201677-61-4) is a potent and selective leukocyte elastase inhibitor, IC50 = 44 nM.1 Displays no activity at a variety of other ...$50.00 – $200.00 Select options -
Angiogenesis
Sorafenib | Multi-kinase inhibitor
Sorafenib (475207-59-1) was initially developed as a Raf kinase inhibitor, IC50 = 6 nM, but has been shown to inhibit many receptor tyrosine kinase...$40.00 – $160.00 Select options -
Approved Drugs
Sulfasalazine | Anti-inflammatory / antibiotic
Sulfasalazine (599-79-1) is an approved drug with diverse potential applications. Sulfasalzine is a clinically useful agent for the treatment of co...$20.00 – $30.00 Select options -
Angiogenesis
Sunitinib malate | VEGFR, PDGFR kinase inhibitor
Sunitinib malate (341031-54-7) is a potent inhibitor of multiple receptor tyrosine kinases including VEGFR, PDGFRβ and Kit (Ki = 2-17 nM)1. Also in...$50.00 – $130.00 Select options -
Approved Drugs
Suplatast tosilate | Immunomodulator
Suplatast tosilate (94055-79-2) is a potent immunoregulator that suppresses IgE production.1 Suppresses innate immunity by down-regulating TLR2, TL...$55.00 – $220.00 Select options -
Approved Drugs
Tafamidis | Transthyretin stabilizer
Tafamidis (594839-88-0) is a potent and selective transthyretin (TTR) kinetic stabilizer. It binds selectively and with negative cooperativity to t...$60.00 – $200.00 Select options
