Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Amlodipine | L-type Ca channel blocker
From $30.00CAS:88150-42-9Catalog Number:10-1210Activity:L-type Ca channel blockerMolecular Weight:408.89Molecular Formula:C20H25ClN2O5Solubility:Soluble in DMSO (up to 25 mg/ml), in DMF (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Amphotericin B | Antifungal agent
From $60.00CAS:1397-89-3Catalog Number:10-2430Activity:Antifungal agentChemical Names:NSC 527017Molecular Weight:924.08Molecular Formula:C47H73NO17Solubility:Soluble in DMSO (18 mg/ml)Physical Properties:Yellow or orange solidPurity:90% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Anagrelide HCl | PDE3 inhibitor
From $48.00CAS:58579-51-4Catalog Number:10-1220Activity:PDE3 inhibitorChemical Name:6,7-dichloro-1,5-dihydroimidazo[2,1 –b]quinazolin-2(3H)-one hydrochlorideAlternate Names:BL-4162AMolecular Weight:292.55Molecular Formula:C10H7Cl2N3O • HClSolubility:Soluble in DMSO (up to 2.5 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Apixaban | Factor Xa inhibitor
From $50.00CAS:503612-47-3Catalog Number:10-5660Activity:Factor Xa inhibitorChemical Names:4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamideMolecular Weight:459.51Molecular Formula:C25H25N5O4Solubility:Soluble in DMSO (40 mg/ml)Physical Properties:White solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Apomorphine HCl | Dopamine agonist
From $50.00CAS:41372-20-7Catalog Number:10-1338Activity:Dopamine agonistChemical Name:(R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinolone-10,11-diol hydrochlorideAlternate Names:R-(-)-6aβ-aporphine-10,11-diol hydrochloride HemihydrateMolecular Weight:312.78Molecular Formula:C17H17NO2• HCl 1/2H2OSolubility:Soluble in Water (up to 20 mg/ml)Physical Properties:Grey solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 week.Shipping Code:RT -
Aprepitant | NK-1 antagonist
From $40.00CAS:170729-80-3Catalog Number:10-4366Activity:NK-1 antagonistChemical Names:3-[[(2R,3S)-2-[(1R)-1-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,4dihydro-1,2,4-triazol-5-oneAlternate Name:MK-0869Molecular Weight:534.43Molecular Formula:C23H21F7N4O3Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
