Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Velpatasvir | Hepatitis C NS5A inhibitor
From $40.00CAS:1377049-84-7Catalog Number:10-4931Activity:Hepatitis C NS5A inhibitorChemical Names:Methyl [(2S)-1-[(2S,5S)-2-[9-[2-[(2S,4S)-1-[(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl]-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4′,3′:6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate; GS-5816Molecular Weight:883.02Molecular Formula:C49H54N8O8Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Pale yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Verapamil HCl | L-type Ca channel blocker
From $27.00CAS:152-11-4Catalog Number:10-1111Activity:L-type Ca channel blockerChemical Name:5-[N-(3,4-Dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochlorideMolecular Weight:491.06Molecular Formula:C27H38N2O4·HClSolubility:Soluble in DMSO (up to 20 mg/ml) or in Water (up to 50 mg/ml).Physical Properties:White solidPurity:>98% by TLCStorage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Vildagliptin Supplier | DPPIV inhibitor
From $44.00CAS:274901-16-5Catalog Number:10-2887Activity:DPP4 inhibitorChemical Name:(S)-1-[N-(3-Hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrileAlternate Names:LAF237Molecular Weight:303.40Molecular Formula:C17H25N3O2Solubility:Soluble in DMSO (up to 45 mg/ml), in DMF (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 3 monthsShipping Code:RT -
Vinblastine sulfate | Microtubule depolymerizer
From $48.00CAS:143-67-9Catalog Number:10-2050Activity:Microtubule depolymerizerAlternate Names:VincaleukoblastineMolecular Weight:909.08Molecular Formula:C46H58N4O9 H2SO4Solubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Stability:Store for up to 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
Vincristine sulfate | Microtubule depolymerizer
From $30.00CAS:2068-78-2Catalog Number:10-2570Activity:Microtubule depolymerizerAlternate Names:Leurocristine sulfateChemical Name:22-Oxovincaleukoblastine sulfateMolecular Weight:923.06Molecular Formula:C46H56N4O10Solubility:Soluble in Water (up to 80 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
Vismodegib | Sonic Hedgehog signaling pathway inhibitor
From $60.00CAS:879085-55-9Catalog Number:10-2182Activity:Sonic Hedgehog signaling pathway inhibitorChemical Name:2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamideAlternate Names:GDC-0449Molecular Weight:421.3Molecular Formula:C19H14Cl2N2O3SSolubility:Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 10 mg/ml with warming)Physical Properties:Off-white or beige solidPurity:99% by TLC and HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT
