Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Trametinib | MEK inhibitor
From $40.00CAS:871700-17-3Catalog Number:10-4759Activity:MEK inhibitorChemical Name:N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamideAlternate Names:GSK1120212Molecular Weight:615.39Molecular Formula:C26H23FIN5O4Solubility:Soluble in DMSO (up to 20 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Tranilast | Antiallergy agent
From $40.00CAS:53902-12-8Catalog Number:10-2234Activity:NFκB inhibitorAlternate Names:RizabenChemical Name:N-(3′,4′-Dimethoxycinnamoyl)anthranilic acidMolecular Weight:327.34Molecular Formula:C18H17NO5Solubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:Pale yellow solidPurity:98% by TLC
NMR (Conforrms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Trifluorothymidine | Proapoptotic antiproliferative agent
From $45.00CAS:70-00-8Catalog Number:10-1283Activity:Thymidylate synthase inhibitor / Anti-cancer agentChemical Name:2’-Deoxy-5-trifluoromethyluridineAlternate Names:α,α,α-Trifluorothymidine; Trifluorothymine deoxyriboside; Trifluridine; TFTMolecular Weight:296.20Molecular Formula:C10H11F3N2O5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT -
Valsartan | Angiotensin antagonist
From $50.00CAS:137862-53-4Catalog Number:10-2052Activity:Angiotensin antagonistAlternate Names:CGP-48933Chemical Name:(S)-3-Methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-pentanamido]butanoic acidMolecular Weight:435.52Molecular Formula:C24H29N5O3Solubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:White solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Varenicline tartrate | α4ß2 partial agonist/Smoking cessation aid
CAS:375815-87-5Catalog Number:10-2362 -
Velpatasvir | Hepatitis C NS5A inhibitor
From $40.00CAS:1377049-84-7Catalog Number:10-4931Activity:Hepatitis C NS5A inhibitorChemical Names:Methyl [(2S)-1-[(2S,5S)-2-[9-[2-[(2S,4S)-1-[(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl]-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4′,3′:6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate; GS-5816Molecular Weight:883.02Molecular Formula:C49H54N8O8Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Pale yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
