Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Allopregnanolone | GABA-A positive allosteric modulator
From $70.00CAS:516-54-1Catalog Number:10-3489Activity:GABA-A positive allosteric modulatorChemical Name:(3α,5α)-3-Hydroxy-pregnan-20-oneAlternate Name:(3α,5α)-Tetrahydroprogesterone; 3-OH-DHPMolecular Weight:318.49Molecular Formula:C21H34O2Solubility:Soluble in DMSO (up to 32 mg/ml) or in Ethanol (up to 32 mg/ml)Physical Properties:White or off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20° (des.)Stability:Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
Altretamine | Ferroptosis inducer
From $35.00CAS:645-05-6Catalog Number:10-5592Activity:Ferroptosis inducer/GPX4 inhibitorChemical Names:N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 2,4,6-Tris(dimethylamino)-1,3,5-triazineAlternate Name:Hexamethylmelamine; NSC-13875Molecular Weight:210.29Molecular Formula:C9H18N6Solubility:Soluble in DMSO (40 mg/ml)Physical Properties:White solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Ambroxol HCl | Free radical scavenger
From $50.00CAS:18683-91-5Catalog Number:10-2296Activity:Free radical scavengerChemical Name:trans-4-(2-Amino-3,5-dibromobenzylamin)cyclohexane _ HClMolecular Weight:414.56Molecular Formula:C13H18Br2N2O HClSolubility:Soluble in Water.Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
AMG 510 |Covalent KRASG12C Inhibitor
From $69.00AMG 510 (2296729-00-3; Sotorasib) is a potent (IC50’s = 6 nM NCI-H358; 9 nM MIA PaCa-2) covalent KRASG12C inhibitor.1,2 It significantly inhibited tumor growth in NCI-H358 and MIA […]
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Amifostine | Cellular protectant
From $56.00CAS:20537-88-6Catalog Number:10-2291Activity:Cellular protectantAlternate Names:WR-2721Chemical Name:S-2(3-Aminopropylamino)-ethylphosphothioic acidMolecular Weight:214.22Molecular Formula:C5H15N2O3PSSolubility:Soluble in Water.Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
Amiodarone HCl | Pan-specific ion channel blocker
$45.00CAS:19774-82-4Catalog Number:10-2468Activity:Pan-specific ion channel blockerChemical Name:2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochlorideMolecular Weight:681.77Molecular Formula:C25H29I2NO3 HClSolubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT
