Approved Drugs
Showing 97–108 of 204 results
-
Antifungals
Ketoconazole | Cytochrome P450 Inhibitor
Ketoconazole (65277-42-1) is a broad spectrum antifungal agent which acts via inhibition of a cytochrome P450, CYP51A1 which is a lanosterol 14α-de...$40.00 – $70.00 Select options -
Antivirals
Lamivudine | Reverse transcriptase inhibitor
Lamivudine (134678-17-4) is a nucleoside analog reverse transcriptase inhibitor.1 A potent and selective inhibitor of human immunodeficiency virus ...$45.00 – $145.00 Select options -
Approved Drugs
Lapatinib (base) | EGFR and HER2 inhibitor
Lapatinib (231277-92-2) is a potent inhibitor of EGFR kinase (Ki=3 nM), Erb-2 kinase (Ki=13 nM) Erb-4 kinase (Ki=347 nM).1 Clinically useful agent...$50.00 – $110.00 Select options -
Approved Drugs
Larotrectinib | TRK inhibitor
Larotrectinib (1223403-58-4) is a potent (IC50’s < 11 nM) inhibitor of tropomyosin receptor kinases A, B, and C (TrkA, B, and C).1 It is >100...$65.00 – $225.00 Select options -
Approved Drugs
Leflunomide | Immunosuppressant
Leflunomide (75706-12-6) pyrimidine biosynthesis inhibitor DMARD (disease-modifying antirheumatic drug).1 Displays immunomodulatory activity inhibi...$40.00 – $160.00 Select options -
Angiogenesis
Lenalidomide | Immunomodulator
Lenalidomide (191732-72-6) is a thalidomide analog which, like thalidomide1, binds to cereblon which is the substrate recognition component of a cu...$35.00 – $70.00 Select options -
Angiogenesis
Lenvatinib | VEGFR inhibitor
Lenvatinib (417716-92-8) is a potent inhibitor of VEGFR2 and R3, IC50s=4.0 and 5.2 nM respectively.1 Also inhibits VEGFR1, FGFR1, PDGFR3b and Kit,...$55.00 – $220.00 Select options -
New Products
Levetiracetam | Anticonvulsant
Levetiracetam (102767-28-2) is a clinically useful non-classical anticonvulsant.1 It has no effect on voltage-dependent Na+ channels, GABAergic tra...$45.00 – $70.00 Select options -
Approved Drugs
Lomerizine | Calcium Channel Blocker
Lomerizine (101477-54-7) is a clinically useful calcium channel blocker (L and T-type). It is used for the treatment of migraine headaches, howeve...$40.00 – $110.00 Select options -
Approved Drugs
Losartan potassium | Angiotensin AT1 antagonist
Losartan potassium (124750-99-8) is a non-peptide angiotensin II receptor antagonist.1,2 Clinically useful antihypertensive agent.3 Inhibits collag...$40.00 – $160.00 Select options -
Approved Drugs
Lovastatin | HMG-CoA reductase inhibitor
Lovastatin (75330-75-5) Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-CoA reductase (Ki=1nM for acid form).1,2 Induces apopt...$50.00 – $165.00 Select options -
Antivirals
Manidipine dihydrochloride | Calcium channel blocker
Manidipine (89226-75-5) is a clinically useful antihypertensive.1,2 It is an inhibitor of L- and T-type calcium channels with high selectivity for ...$25.00 – $50.00 Select options
