Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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Argatroban | Thrombin inhibitor
From $56.00CAS:74863-84-6Catalog Number:10-2809Activity:Thrombin inhibitorAlternate Names:Argidipine; MQPAChemical Name:(2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acidMolecular Weight:508.63Molecular Formula:C23H36N6O5SSolubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
Aripiprazole | Dopamine receptor partial agonist
From $40.00CAS:129722-12-9Catalog Number:10-2314Activity:Dopamine receptor partial agonistAlternate Names:OPC-14597Chemical Name:7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinoneMolecular Weight:448.4Molecular Formula:C23H27Cl2N3O2Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 5 mg/ml with warming).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Atazanavir | HIV protease inhibitor
From $65.00CAS:198904-31-3Catalog Number:10-5630Activity:HIV protease inhibitorChemical Names:Methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamateAlternate Name:BMS 232632; CGP 73547; LatazanavirMolecular Weight:704.87Molecular Formula:C38H52N6O7Solubility:Soluble in DMSO (45 mg/ml)Physical Properties:White to off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Auranofin | IKK inhibitor
$50.00CAS:34031-32-8Catalog Number:10-2373Activity:IKK inhibitorAlternate Names:SKF-39162Chemical Name:1-Thio-β-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetateMolecular Weight:678.49Molecular Formula:C20H34AuO9PSSolubility:Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 4 mg/ml).Physical Properties:White solidPurity:98%Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT -
Axitinib | VEGFR kinase inhibitor
From $40.00CAS:319460-85-0Catalog Number:10-2118Activity:VEGFR kinase inhibitorChemical Name:N-Methyl-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamideMolecular Weight:386.47Molecular Formula:C22H18N4OSSolubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Baricitinib | JAK 1/2 inhibitor
From $48.00CAS:1187594-09-7Catalog Number:10-3893Activity:JAK 1/2 inhibitorChemical Name:1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidine-acetonitrileAlternate Name:INCB028050; LY3009104Molecular Weight:371.42Molecular Formula:C16H17N7O2SSolubility:Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 50 mg/ml).Physical Properties:White or off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.Shipping Code:RT
