Cytokine modulators
Cytokines are a diverse group of small proteins comprising interleukins, interferons, chemokines, lymphokines, and tumor necrosis factors (TNF). Not only are they key players in inflammation and immune response, but they also have roles in wound healing, cell cycling and death, and cancer progression. Their receptors are just as diverse, being immunoglobulins and transmembrane proteins that transmit signals via kinases and GPCRs.
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Tryptanthrin | Immunomodulator/IDO2 inhibitor
From $55.00CAS:13220-57-0Catalog Number:10-2228Activity:Immunomodulator; IDO2 inhibitorChemical Name:Indolo(2,1-b)quinazoline-6,12-dioneAlternate Names:NSC 349447; Couroupitine AMolecular Weight:248.24Molecular Formula:C15H8N2O2Solubility:Soluble in DMSO (up to 24 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
VGX-1027 | Immunomodulator; Cytokine release inhibitor
From $50.00CAS:6501-72-0Catalog Number:10-3409Activity:Immunomodulator; Cytokine release inhibitorChemical Name:4,5-Dihydro-3-phenyl-5-isoxazoleacetic acidAlternate Name:GIT 27Molecular Weight:205.21Molecular Formula:C11H11NO3Solubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
