Focus on elimination of senescent cancer cells. Researchers at the Netherlands Cancer Institute just reported in PNAS that SLC25A23 (involved in mitochondrial transmembrane transport) is a […]
Science’s 2024 “Breakthrough of the Year” is Gilead’s drug Lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 […]
Focus on Drug Approvals. This week the FDA approved Ensartinib for ALK-positive locally advanced or metastatic non-small cell lung cancer. Ensartinib is a potent and specific […]
Focus on Drug Approvals. The FDA has approved Syndax Pharmaceuticals’ Revumenib (SNDX-5613, inhibitor of menin-KMT2A interaction) for relapsed or refractory acute leukemia with lysine methyltransferase 2A […]
Is coffee good for your brain? N-Eicosanoyl-serotonin (EHT), a novel natural product found in coffee, has been shown to have a protective effect in models of […]
Focus on Drug Discovery. A biopharmaceutical company called Soligenix is developing the natural product hypericin as a treatment for cutaneous T-cell lymphoma. Hypericin, applied as a […]
Journal Club. Paul Rosenfeld and coworkers at the University of Toronto recently reported in the journal Viruses that Rocaglamide, a structurally novel natural product, inhibits HIV-1 […]
The journal Cell is celebrating 50 years of metabolism research with a special Focus on Metabolism, illustrating its importance in so many processes and diseases. […]
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