August 1, 2022
Yan and coworkers have demonstrated a potential way to boost innate immune attack on solid tumors. They found that Rocaglamide, a structurally novel natural product, promoted […]
June 24, 2022
Lipid raft dynamics regulate signaling for multiple cellular functions, such as apoptosis, proliferation, and differentiation. They reside in the plasma membrane and comprise sphingolipids, cholesterol, and […]
June 22, 2022
Kumar et al. and Zijlmans et al. have published in Nature Cell Biology that Polycomb repressive complex 2 (PRC2) epigenetically reduces lineage potential of hESCs. They […]
June 15, 2022
JTE-607, a cell-permeable prodrug which is converted to its active COOH form via intracellular esterases, was originally found to inhibit cytokine release but its mechanism of […]
June 3, 2022
A team headed by distinguished neuroscientist Alcino Silva recently showed that expression of C-C chemokine receptor type 5 (CCR5) expression reduced memory recall, and maraviroc (Focus […]
May 23, 2022
Perylenequinones are a family of structurally novel fungal or plant natural products which act as photosensitizers. They absorb light energy, enabling them to generate reactive oxygen […]
May 12, 2022
In Nature Communications, Zhang et al. show that DJ001, a selective allosteric inhibitor of protein tyrosine phosphatase sigma (PTPσ), promotes hematopoietic stem cell (HSC) regeneration. Treatment […]
