March 30, 2023
Journal Club: Surfactin is a cyclic lipopeptide microbial metabolite produced by Bacillus subtilis that acts as a biosurfactant among other interesting activities. S.C. Yang and coworkers […]
March 30, 2023
In The News: Bempedoic acid is an FDA-approved drug for the treatment of hypercholesterolemia sold under the brand name Nexletol. It is an ATP citrate lyase […]
March 23, 2023
Focus on Drug Discovery: Saridegib is a natural product-inspired drug candidate. Its prototype, cyclopamine was discovered as a teratogenic steroidal alkaloid that was found to cause […]
March 23, 2023
Journal Club: Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder caused by the expression of progerin, a Lamin A mutant. The study of HGPS […]
March 23, 2023
Journal Club: In a paper just out in PNAS, Y. Lin and coworkers showed that Eltrombopag, an FDA-approved drug for thrombocytopenia, inhibits autophagy by targeting the […]
March 23, 2023
Journal Club: A paper just out in J. Proteomics by Herman Sintim and coworkers at Purdue sheds new light on the signaling roles of the cyclic […]
March 23, 2023
In The News: Bempedoic acid is an FDA-approved drug for the treatment of hypercholesterolemia sold under the brand name Nexletol. It is an ATP citrate lyase […]
February 10, 2023
J Zhang and coworkers at Leiden University Med Ctr have shown that a splice variant of the ubiquitin specific protease, USP19-CY, can enhance the epithelial-mesenchymal transition […]
January 25, 2023
In a paper just out in Phytomedicine, HG Kim and coworkers describe the in vitro anti-cancer activity of Beauvericin, an antimicrobial metabolite from the fungus Beauveria […]
