November 28, 2022

Focus Biomolecules at ASCB Cell Biology

Focus will be exhibiting at ASCB Cell Biology, Dec 3-7 in Washington DC. Stop by our booth #2205 and chat with our scientists! Learn about our […]
November 28, 2022

Filipin III for Cholesterol Research

Filipin III is a microbial natural product isolated from Streptomyces filipinensis. It is an important fluorescent probe for cellular cholesterol detection. In addition, because it binds […]
November 22, 2022

Sinefungin in Antiviral Research

Two recent papers employed Sinefungin in determination of the structure of two different viral methyltransferases. Sinefungin is a Streptomyces natural product analog of S-adenosylmethionine acting as […]
October 14, 2022

SSRIs block SARS-CoV-2 protease in silico

In a molecular docking analysis, Tronco Pauletto et al. found that antidepressants such as fluoxetine, citalopram, and norfluoxetine likely interact with and disrupt SARS-CoV-2 main protease […]
October 14, 2022

Obesity research news

Carlos Guijas and coworkers at Scripps recently found that the leukotriene antagonist and antiasthmatic agent zafirlukast was able to differentiate adipocyte precursors into functional brown adipocytes. […]
September 23, 2022

Romidepsin attenuates growth of rare sarcomas

Yuki Yoshimatsu and coworkers have shown that they could establish patient-derived cancer cell lines for myxofibrosarcoma and pleomorphic sarcoma. After screening these cell lines with a […]
September 20, 2022

BAM15 attenuates sepsis hyperinflammation

P. Hiengrach and coworkers recently showed that BAM15, a mitochondrial uncoupling agent, attenuated sepsis in a mouse cecal ligation and puncture model. BAM15 attenuated sepsis as […]
September 15, 2022

Inducing Autophagy Against Mycobacterial Infection

Activation of autophagy is a novel mode of therapeutic intervention and offers the possibility of developing new “host-directed” therapeutics against mycobacterial infection. For example, Kim et […]
September 12, 2022

Lifespan Extension by Rapamycin

Paula Juricic and coworkers at the Max Planck Institute for Biology of Ageing report in a recent issue of Nature Aging that a brief early treatment […]