Metals and biological systems
Many enzymes and systems depend on metal ions, such as zinc, iron, and copper, for proper function. These include proteases (active site function), hemoglobins (carrying oxygen), cytochromes (electron transfer), free radical control, and metal ion storage. Chelators sequester metal ions, offering a way to control or block these functions, which can be useful in infectious disease, wound healing, and heavy metal poisoning, and research in metal-dependent processes such as ferroptosis, cuproptosis, and oxidative stress.
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Ferrostatin-1 | Ferroptosis inhibitor
From $45.00CAS:347174-05-4Catalog Number:10-1380Activity:Ferroptosis inhibitorChemical Name:Ethyl 3-amino-4-(cyclohexylamino)benzoateMolecular Weight:262.35Molecular Formula:C15H22N2O2Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).Physical Properties:Tan solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
Hinokitiol | Iron Chelator antioxidant
From $52.00CAS:499-44-5Catalog Number:10-2211Activity:Iron Chelator antioxidantAlternate Names:β-ThujaplicinChemical Name:2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-oneMolecular Weight:164.2Molecular Formula:C10H12O2Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:White solidPurity:>98%Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.Shipping Code:RT -
Liproxstatin-1 | Ferroptosis inhibitor
From $55.00CAS:950455-15-9Catalog Number:10-4670Activity:Ferroptosis inhibitorChemical Names:N-[(3-Chlorophenyl)methyl]spiro[1,4-dihydroquinoxaline-3,4’-piperidine]-2-amineMolecular Weight:340.85Molecular Formula:C19H21ClN4Solubility:Soluble in DMSO (15 mg/ml)Physical Properties:White to off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month.Shipping Code:RT -
ML210 | GPX4 inhibitor / Ferroptosis inducer
From $85.00CAS:1360705-96-9Catalog Number:10-4002Activity:GPX4 inhibitor / Ferroptosis inducerChemical Name:(4-(Bis(4-chlorophenyl)methyl)piperazine-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanoneMolecular Weight:475.32Molecular Formula:C22H20Cl2N4O4Solubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
