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Phosphodiesterases

  • Rolipram | PDE4 inhibitor

    CAS:
    61413-54-5
    Catalog Number:
    10-1079
    Activity:
    PDE4 inhibitor
    Alternate Names:
    ZK 62711
    Chemical Name:
    4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone (racemic)
    Molecular Weight:
    275.35
    Molecular Formula:
    C16H21NO3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR conforms
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $48.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Sulindac Sulfide | NFkappaB inhibitor

    CAS:
    49627-27-2
    Catalog Number:
    10-2156
    Activity:
    NFkappaB inhibitor
    Chemical Name:
    (Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid
    Molecular Weight:
    340.42
    Molecular Formula:
    C20H17FO2S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Sulindac Sulfone | Modulates beta-catenin-mediated effects

    CAS:
    59864-04-9
    Catalog Number:
    10-1122
    Activity:
    Modulates beta-catenin-mediated effects
    Chemical Name:
    (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid
    Molecular Weight:
    372.41
    Molecular Formula:
    C20H17FO4S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Vinpocetine | PDE1 inhibitor

    CAS:
    42971-09-5
    Catalog Number:
    10-1126
    Activity:
    PDE1 inhibitor
    Chemical Name:
    (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
    Molecular Weight:
    350.45
    Molecular Formula:
    C22H26N2O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml), in ethanol (up to 15 mg/ml) or in DMF (up to 3 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, Ethanol, or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
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