Histone Demethylation

  • IOX 1 | JMJD demethylase inhibitor

    CAS:
    5852-78-8
    Catalog Number:
    10-1426
    Activity:
    JMJD demethylase inhibitor
    Alternate Names:
    5-Carboxy-8HQ
    Chemical Name:
    8-Hydroxy-5-quinolinecarboxylic acid
    Molecular Weight:
    189.17
    Molecular Formula:
    C10H7NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $72.00
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  • iPHF8 | Inhibitor of lysine demethylase PHF8

    CAS:
    1574530-99-6
    Catalog Number:
    10-4049
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  • JIB-04 | pan-JUMONJI histone demethylase inhibitor

    CAS:
    199596-05-9
    Catalog Number:
    10-1618
    Activity:
    pan-JUMONJI histone demethylase inhibitor
    Chemical Name:
    (E)-5-Chloro-2-(2-(phenyl(pyridine-2-yl)methylene)hydrazinyl)pyridine
    Molecular Weight:
    308.76
    Molecular Formula:
    C17H13ClN4
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • ML324 | JMJD2 inhibitor

    CAS:
    1222800-79-4
    Catalog Number:
    10-1455
    Activity:
    JMJD2 inhibitor
    Chemical Name:
    N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide
    Molecular Weight:
    349.43
    Molecular Formula:
    C21H23N3O2
    Solubility:
    Soluble in DMSO (10 mg/ml).
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • PBIT | JARID1 lysine demethylase inhibitor

    CAS:
    2514-30-9
    Catalog Number:
    10-1595
    Activity:
    JARID1 lysine demethylase inhibitor
    Chemical Name:
    2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-one
    Molecular Weight:
    241.31
    Molecular Formula:
    C14H11NOS
    Solubility:
    Soluble in DMSO (up to 24 mg/ml) or in Ethanol (up to 5 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $62.00
    View Product This product has multiple variants. The options may be chosen on the product page
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