Glyco processing

Glycosylation is the enzymatic addition of carbohydrate chains to proteins or lipids in cells. Carbohydrate chains vary greatly in composition and length and are often branched. Glycosylation (and deglycosylation) play roles in protein and lipid conformation, interaction, function, and stability.

Glucosidase

  • Miglustat HCl | Alpha-glucosidase inhibitor
    CAS:
    210110-90-0
    Catalog Number:
    10-2413
    Activity:
    Alpha-glucosidase inhibitor
    Chemical Name:
    N-Butyldeoxynojirimycin HCl
    Alternate Names:
    NB-DNJ
    Molecular Weight:
    255.74
    Molecular Formula:
    C10H21NO4 • HCL
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Isofagomine tartrate | Glucocerebrosidase activator and chaperone
    CAS:
    957230-65-8
    Catalog Number:
    10-2859
    Activity:
    Glucocerebrosidase activator and chaperone
    Chemical Name:
    (3R,4R,5R)-5-Hydroxymethyl-3,5-piperidinediol tratrate
    Molecular Weight:
    297.26
    Molecular Formula:
    C6H13NO3 • C4H6O6
    Solubility:
    Soluble in DMSO (up to 2 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Deoxynojirimycin | Glucosidase inhibitor
    CAS:
    19130-96-2
    Catalog Number:
    10-2409
    Activity:
    Glucosidase inhibitor
    Chemical Name:
    (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol
    Molecular Weight:
    163.17
    Molecular Formula:
    C6H13NO4
    Solubility:
    Soluble in Water up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • Miglitol | beta-glucosidase inhibitor / antidiabetic
    CAS:
    72432-03-2
    Catalog Number:
    10-2332
    Activity:
    α-glucosidase inhibitor / antidiabetic
    Alternate Names:
    N-(2-Hydroxyethyl)-1-deoxynojirimycin; BAY-1099
    Chemical Name:
    (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
    Molecular Weight:
    207.23
    Molecular Formula:
    C8H17NO5
    Solubility:
    Soluble in DMSO (up to 50 mg/ml with warming), or in Water (up to 60 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Conduritol B epoxide | Glycosidase inhibitor
    CAS:
    6090-95-5
    Catalog Number:
    10-1172
    Activity:
    β-Glycosidase inhibitor
    Alternate Names:
    CBE
    Chemical Name:
    D,L-1,2-Anhydro-myo-inositol
    Molecular Weight:
    162.14
    Molecular Formula:
    C6H10O5
    Solubility:
    Soluble in Water (up to 25 mg/ml) or in DMSO
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Compound is hygroscopic, protect from moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
View All Glucosidase Products

Mannosidase

  • Deoxymannojirimycin HCl | Mannosidase inhibitor
    CAS:
    73465-43-7
    Catalog Number:
    10-2798
    Activity:
    Mannosidase inhibitor
    Chemical Name:
    2R-(Hydroxymethyl)-3R,4R,5R-piperidinetriol hydrochloride
    Alternate Names:
    1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride
    Molecular Weight:
    199.63
    Molecular Formula:
    C6H13NO4 • HCl
    Solubility:
    Soluble in Water (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • Kifunensine | Mannosidase inhibitor
    CAS:
    109944-15-2
    Catalog Number:
    10-2860
    Activity:
    Mannosidase inhibitor
    Chemical Name:
    (5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione
    Alternate Names:
    FR-900494
    Molecular Weight:
    232.19
    Molecular Formula:
    C8H12N2O6
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Swainsonine | Glycosidase inhibitor
    CAS:
    72741-87-8
    Catalog Number:
    10-2674
    Activity:
    Glycosidase inhibitor
    Chemical Name:
    (1S,2R,8R,8aR)-octahydro-1,2,8-indolizinetriol
    Molecular Formula:
    C8H15NO3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml), in Ethanol (up to 10 mg/ml) or in Water (up to 8 mg/ml)
    Physical Properties:
    White or off-white solid solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
View All Mannosidase Products

Other Glycoprocessing

  • Migalastat HCl | Galactosidase inhibitor/Pharmacological chaperone
    CAS:
    75172-81-5
    Catalog Number:
    10-2632
  • 4-MUG | ß-Galactosidase fluorogenic substrate
    CAS:
    6160-78-7
    Catalog Number:
    10-3879
    Activity:
    ß-Galactosidase fluorogenic substrate
    Chemical Names:
    4-Methylumbelliferyl ß-D-galactopyranoside;
    4-MU-b-D-Gal; MUgal; MUG; MUGA
    Molecular Weight:
    338.31
    Molecular Formula:
    C16H18O8
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    97% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • IPTG (animal free) | Induces ß-galactosidase in bacteria
    CAS:
    367-93-1
    Catalog Number:
    10-2394
    Activity:
    Induces β-galactosidase in bacteria
    Chemical Name:
    Isopropyl β-D-thiogalactopyranoside (non-animal origin)
    Molecular Weight:
    238.3
    Molecular Formula:
    C9H18O5S
    Solubility:
    Soluble in Water or Methanol.
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)Lead < 2ppm
    Dioxane – not detected
    Water – 0.38% (Karl Fischer)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water or methanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
View All Other Glycoprocessing Products

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