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DNA Damage Response

  • AZ20 | ATR kinase inhibitor

    CAS:
    1233339-22-4
    Catalog Number:
    10-4675
    Activity:
    ATR kinase inhibitor
    Chemical Name:
    4-{4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl}-1H-indole
    Molecular Weight:
    412.51
    Molecular Formula:
    C21H24N4O3S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $55.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • AZD7648 | DNA-PK inhibitor/CRISPR enhancer

    CAS:
    2230820-11-6
    Catalog Number:
    10-4108
    View Product This product has multiple variants. The options may be chosen on the product page

  • BML-277 | CHK2 inhibitor

    CAS:
    516480-79-8
    Catalog Number:
    10-1024
    Activity:
    CHK2 inhibitor
    Chemical Name:
    2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
    Molecular Weight:
    363.81
    Molecular Formula:
    C20H14ClN3O2
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR conforms
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • KU-55933 | ATM Kinase Inhibitor

    CAS:
    587871-26-9
    Catalog Number:
    10-1518
    Activity:
    ATM Kinase Inhibitor
    Chemical Name:
    2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one
    Molecular Weight:
    395.5
    Molecular Formula:
    C21H17NO3S2
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • LY2603618 | Potent and selective Chk1 inhibitor

    CAS:
    911222-45-2
    Catalog Number:
    10-4123
    Activity:
    Potent and selective Chk1 inhibitor
    Chemical Name:
    N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N’-(5-methyl-2-pyrazinyl)urea
    Alternate Names:
    Rabusertib
    Molecular Weight:
    436.30
    Molecular Formula:
    C18H22BrN5O3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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