Highly Selective Inhibitors
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Binimetinib | MEK1/2 inhibitor
From $39.00CAS:606143-89-9Catalog Number:10-4789Activity:MEK1/2 inhibitorChemical Name:6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamideAlternate Names:ARRY-162; MEK162Molecular Weight:441.23Molecular Formula:C17H15BrF2N4O3Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Duvelisib | PI3Kdelta/gamma inhibitor
From $65.00CAS:1201438-56-3Catalog Number:10-4788Activity:PI3Kδ/γ inhibitor/Cancer immunotherapy enhancerChemical Name:8-Chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-oneAlternative Name:IPI-145Molecular Weight:416.87Molecular Formula:C22H17ClN6OSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Fruquintinib | Potent and selective inhibitor of VEGFR kinase
From $60.00CAS:1194506-26-7Catalog Number:10-4784Activity:Potent and selective inhibitor of VEGFR kinaseChemical Name:6-(6,7-Dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamideAlternate Name:HMPL-013Molecular Weight:393.40Molecular Formula:C21H19N3O5Solubility:Soluble in DMSO (up to 5 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
Glumetinib | Highly selective c-Met inhibitor
From $90.00CAS:1642581-63-2Catalog Number:10-4690Activity:Highly selective c-Met inhibitorChemical Names:6-(1-Methylpyrazol-4-yl)-1-[6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-yl]sulfonylpyrazolo[4,3-b]pyridine: SCC244Molecular Weight:459.48Molecular Formula:C21H17N9O2SSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:Beige solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
