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Immunoregulatory

  • Acalabrutinib | Highly selective BTK inhibitor

    CAS:
    1420477-60-6
    Catalog Number:
    10-4806
    Alternate Name:
    ACP-196
    Activity:
    Highly selective BTK inhibitor
    Chemical Name:
    4-[8-Amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
    Molecular Weight:
    465.52
    Molecular Formula:
    C26H23N7O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)

     

    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Apilimod | IL-12 and 23/PIKfyve inhibitor

    CAS:
    541550-19-0
    Catalog Number:
    10-4970
    Activity:
    IL-12 and 23/PIKfyve inhibitor
    Chemical Names:
    N-[(E)-(3-Methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine; STA5326
    Molecular Weight:
    418.50
    Molecular Formula:
    C23H26N6O2
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $35.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • AZD1208 | pan-PIM kinase inhibitor

    CAS:
    1204144-28-4
    Catalog Number:
    10-4781
    View Product This product has multiple variants. The options may be chosen on the product page

  • Belumosudil | ROCK2 Inhibitor

    CAS:
    911417-87-3
    Catalog Number:
    10-4165
    Activity:
    Selective Rho kinase 2 (ROCK2) inhibitor
    Chemical Names:
    2-[3-[4-(1H-Indazol-5-yl)amino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide; KD025; SLx-2119
    Molecular Weight:
    452.52
    Molecular Formula:
    C26H24N6O2
    Solubility:
    Soluble in DMSO (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied from date of purchase. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Defactinib | Potent FAK inhibitor

    CAS:
    1073154-85-4
    Catalog Number:
    10-4828
    Activity:
    Potent FAK inhibitor
    Chemical Name:
    N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamide
    Molecular Weight:
    510.50
    Molecular Formula:
    C20H21F3N8O3S
    Solubility:
    Soluble in DMSO (up to at least 25mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
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