Immunoregulatory
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Pexidartinib | CSF1R inhibitor
From $45.00CAS:1029044-16-3Catalog Number:10-4829Activity:CSF1R inhibitor/Cancer immunotherapy enhancerChemical Name:5-[(5-Chloro-1H-pyrrolo[2,3.b]pyridine-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amineAlternate Names:PLX3397Molecular Weight:417.81Molecular Formula:C20H15ClF3N5Solubility:Soluble in DMSO (up to at least 10 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
R428 | Potent and selective AXL inhibitor
From $75.00CAS:1037624-75-1Catalog Number:10-4676Activity:Potent and selective AXL inhibitorChemical Name:1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamineAlternate Names:Bemcentinib; BGB324Molecular Weight:506.64Molecular Formula:C30H34N8Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
SC-514 | IKK-2 inhibitor
From $65.00CAS:354812-17-2Catalog Number:10-1054Activity:IKK-2 inhibitorChemical Name:5-(Thien-3-yl)-3-aminothiophene-2-carboxamideMolecular Weight:224.3Molecular Formula:C9H8N2OS2Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Sitravatinib | Multikinase inhibitor / Immuno-oncology agent
From $50.00CAS:1123837-84-2Catalog Number:10-4826Activity:Multikinase inhibitor / Immuno-oncology agentChemical Name:1-N’-[3-Fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideAlternate Names:MGCD516Molecular Weight:629.68Molecular Formula:C33H29N5O4SSolubility:Soluble in DMSO (up to at least 25 mg/ml), or in Ethanol (up to at least 25 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT
