JAK

  • Ruxolitinib | JAK inhibitor

    CAS:
    941678-49-5
    Catalog Number:
    10-4511
    Activity:
    JAK inhibitor
    Alternate Names:
    INCB 018424
    Chemical Name:
    βR-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
    Molecular Weight:
    306.37
    Molecular Formula:
    C17H18N6
    Solubility:
    Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Tofacitinib | JAK inhibitor

    CAS:
    477600-75-2
    Catalog Number:
    10-2177
    Activity:
    JAK inhibitor
    Alternate Names:
    Tasocitinib, CP-690550
    Molecular Weight:
    312.37
    Molecular Formula:
    C16H20N6O
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by HPLC and TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • WHI-P131 | JAK3 inhibitor

    CAS:
    202475-60-3
    Catalog Number:
    10-1190
    Activity:
    JAK3 inhibitor
    Alternate Names:
    JANEX-1
    Chemical Name:
    4-[(4′-Hydroxyphenyl)amino]-6,7-dimethoxyquinazoline
    Molecular Weight:
    333.78
    Molecular Formula:
    C16H15N3O3·HCl
    Solubility:
    Soluble in DMSO (up to 50 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • WP1066 | JAK2/STAT3 inhibitor

    CAS:
    857064-38-1
    Catalog Number:
    10-4831
    Activity:
    JAK2/STAT3 inhibitor
    Chemical Name:
    (E)-3-(6-Pyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide
    Molecular Weight:
    356.22
    Molecular Formula:
    C17H14BrN3O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $79.00
    View Product This product has multiple variants. The options may be chosen on the product page
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