PI3K

  • GDC-0941 | pan-PI3K inhibitor

    CAS:
    957054-30-7
    Catalog Number:
    10-2141
    Activity:
    pan-Class I PI3-kinase inhibitor
    Chemical Names:
    4-[2-(1H-Indazol-4-yl)-6-[(4-methylsulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine; Pictilisib
    Molecular Weight:
    513.64
    Molecular Formula:
    C23H27N7O3S2
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White/off-white solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $58.00
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  • GSK2636771 | Potent and selective inhibitor of PI3Kß

    CAS:
    1372540-25-4
    Catalog Number:
    10-4172
    View Product This product has multiple variants. The options may be chosen on the product page
  • Idelalisib | Selective PI3Kδ Inhibitor

    CAS:
    870281-82-6
    Catalog Number:
    10-4820
    Activity:
    Selective PI3Kδ Inhibitor
    Chemical Name:
    5-Fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
    Alternate Names:
    CAL-101
    Molecular Weight:
    415.43
    Molecular Formula:
    C21H18FN7O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent

    CAS:
    1693758-51-8
    Catalog Number:
    10-4827
    Activity:
    Selective PI3K-gamma inhibitor / Immuno-oncology agent
    Chemical Name:
    (S)-2-Amino-N-[1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    Molecular Weight:
    629.68
    Molecular Formula:
    C30H24N8O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • LY 294002 | PI 3-Kinase inhibitor

    CAS:
    154447-36-6
    Catalog Number:
    10-2150
    Activity:
    PI 3-Kinase inhibitor
    Chemical Name:
    2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
    Molecular Weight:
    307.34
    Molecular Formula:
    C19H17NO3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white to pale yellow solid
    Purity:
    >98%
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
    From $38.00
    View Product This product has multiple variants. The options may be chosen on the product page
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