Chemotherapeutics

  • Actinomycin D | Transcription inhibitor

    CAS:
    50-76-0
    Catalog Number:
    10-2054
    Activity:
    Transcription inhibitor
    Molecular Weight:
    1255.42
    Molecular Formula:
    C62H86N12O16
    Solubility:
    Soluble in DMSO (50 mg/ml).
    Physical Properties:
    Orange-red solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Protect from exposure to light and moisture. Solutions are not stable and must be made fresh and used within one working day. Do not store solutions.
    Shipping Code:
    RT
    From $60.00
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  • Afatinib | EGFR and HER2 inhibitor

    CAS:
    850140-72-6
    Catalog Number:
    10-4510
    Activity:
    EGFR and HER2 inhibitor
    Chemical Name:
    N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide
    Alternate Names:
    BIBW2992
    Molecular Weight:
    485.94
    Molecular Formula:
    C24H25ClFN5O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
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  • Alectinib | Potent and selective ALK inhibitor

    CAS:
    1256580-46-7
    Catalog Number:
    10-4793
    Activity:
    Potent and selective ALK inhibitor
    Chemical Name:
    9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
    Alternate Name:
    CH5424802
    Molecular Weight:
    482.62
    Molecular Formula:
    C30H34N4O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.
    Shipping Code:
    RT
    From $60.00
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  • Altretamine | Ferroptosis inducer

    CAS:
    645-05-6
    Catalog Number:
    10-5592
    Activity:
    Ferroptosis inducer/GPX4 inhibitor
    Chemical Names:
    N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 2,4,6-Tris(dimethylamino)-1,3,5-triazine
    Alternate Name:
    Hexamethylmelamine; NSC-13875
    Molecular Weight:
    210.29
    Molecular Formula:
    C9H18N6
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $35.00
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  • AMG 510 |Covalent KRASG12C Inhibitor

    CAS:
    2296729-00-3
    Catalog Number:
    10-3930
    View Product This product has multiple variants. The options may be chosen on the product page
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