DNA Damage/Repair
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Olaparib | PARP1 inhibitor
From $45.00CAS:763113-22-0Catalog Number:10-2154Activity:PARP1 inhibitorChemical Name:4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-oneAlternate Names:AZD-2281; KU-59436Molecular Weight:434.47Molecular Formula:C24H23FN4O3Solubility:Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT -
PJ-34 HCl | PARP1/2 inhibitor
From $56.00CAS:344458-15-7Catalog Number:10-2395Activity:PARP1,2 inhibitorChemical Name:N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochlorideMolecular Weight:331.81Molecular Formula:C17H17N3O2Solubility:Soluble in DMSO (up to 30 mg/ml) or in Water (up to 20 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RT (des.)Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.Shipping Code:RT -
RI-1 | RAD51 inhibitor
From $52.00CAS:415713-60-9Catalog Number:10-1617Activity:RAD51 inhibitorChemical Name:3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dioneMolecular Weight:361.61Molecular Formula:C14H11Cl3N2O3Solubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 10 mg/ml with warming)Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
RK-33 | DDX3 inhibitor
From $50.00CAS:1070773-09-9Catalog Number:10-4839Activity:DDX3 inhibitorChemical Name:3,7-Bis(4-methoxybenzyl)-3,7-dihydro-1,3,4,6,7,9-hexaza-2H-cyclopenta[e]azulene-2-oneMolecular Weight:428.44Molecular Formula:C23H20N6O3Solubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
RS-1 | RAD51 activator / CRISPR enhancer
From $50.00CAS:312756-74-4Catalog Number:10-4099Activity:RAD51 activators / CRISPR enhancerChemical Name:4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamideMolecular Weight:524.23Molecular Formula:C20H16BrN2O3SSolubility:Soluble in DMSO (up to 30 mg/ml)Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
- Wnt/ß-Catenin
