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Drug resistance

  • Quizartinib | Selective FLT3 Inhibitor

    CAS:
    950769-58-1
    Catalog Number:
    10-4813
    Activity:
    Selective FLT3 inhibitor
    Chemical Name:
    1-(5-(t-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea
    Alternate Names:
    AC220
    Molecular Weight:
    560.67
    Molecular Formula:
    C29H32N6O4S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • R428 | Potent and selective AXL inhibitor

    CAS:
    1037624-75-1
    Catalog Number:
    10-4676
    Activity:
    Potent and selective AXL inhibitor
    Chemical Name:
    1-(3,4-Diazatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-5-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine
    Alternate Names:
    Bemcentinib; BGB324
    Molecular Weight:
    506.64
    Molecular Formula:
    C30H34N8
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • S-Farnesyl-L-cysteine methyl ester | Multidrug resistance transporter activator

    CAS:
    125741-64-2
    Catalog Number:
    10-4608
    Activity:
    Multidrug resistance transporter activator
    Chemical Name:
    (2R)-2-Amino-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylpropanoic acid methyl ester
    Molecular Weight:
    339.54
    Molecular Formula:
    C19H33NO2S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml)
    Physical Properties:
    Pale yellow oil
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • S07-2010 chemical structure Focus Biomolecules

    S07-2010 | pan-AKR1C inhibitor

    CAS:
    1223194-71-5
    Catalog Number:
    10-4148
    View Product This product has multiple variants. The options may be chosen on the product page

  • Salinomycin Na | Cancer stem cell inhibitor

    CAS:
    55721-31-8
    Catalog Number:
    10-2654
    Activity:
    Cancer stem cell inhibitor
    Chemical Name:
    from Streptomyces albus
    Molecular Weight:
    772.98
    Molecular Formula:
    C42H69O11 Na
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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